Latex-specific IgE

Latex-specific IgE

CPT Test code: 86003

Related Documents:
Test Includes: Avocado; banana; chestnut; kiwi; latex
Specimen: Serum
Volume: 1 mL
Minimum Volume: 0.5 mL (Note: This volume does not allow for repeat testing.)
Container: One 8.5 mL red-top tube or one 8.5 mL gel-barrier tube
Storage Instructions: Refrigerate
Causes for Rejection: Recently administered isotopes; improper labeling; gross hemolysis
Additional Information: The oral allergy syndrome (OAS), also referred to as the pollen-food allergy syndrome,1 is a unique form of food allergy characterized by a localized reaction of the mouth and throat that occurs when affected individuals eat certain fresh fruits and vegetables.2 Patients with allergy to latex will also often have allergies to one or more food allergens including banana, kiwi, avocado, and chestnut. Individuals with OAS experience contact urticaria (itching and hives) that is confined almost exclusively to the mouth and throat upon ingestion of the triggering food. This condition only rarely affects other target organs.2 Characteristic symptoms of OAS include itching of the lips, palate, tongue, and throat.2 OAS is a self-limiting condition with symptoms that occur immediately on contact with foods and typically resolve rapidly. It is important to differentiate these symptoms from systemic and life-threatening allergic throat constricting reactions that can occur during anaphylaxis. It is interesting to note that individuals with OAS to certain food groups frequently suffer from allergy to related nonfood allergens. Allergy to certain nonfood allergens (such as pollens) appears to predispose individuals for the development of associated food allergy.2
Footnotes: 1. Sampson HA. Food Allergy−Accurately Identifying Clinical Reactivity. Allergy. 2005; 60(Suppl 79):19-24. PubMed 15842229

2. American Academy of Allergy, Asthma, and Immunology, The Allergy Report. Milwaukee, Wis: AAAAI; 2000.