10 mL amniotic fluid or 20 mg CVS and 5 mL blood per parental sample
Minimum Volume:
5 mL amniotic fluid or 10 mg CVS and 2 mL blood per parental sample.
Container:
Sterile plastic conical tube or two confluent T-25 flasks and lavender-top (EDTA) tube
Special Instructions:
This test is for fetal/prenatal cases and parental controls. It is not intended for routine sickle cell screening. Please call 800-345-4363 with any questions regarding selection of tests.
Collection:
Do not use urine container, syringes, or tubes with rubber-stoppers. Rubber is toxic to amniocytes.
Storage Instructions:
Maintain specimen at room temperature.
Causes for Rejection:
Specimen frozen; specimen found not to be amniotic fluid; quantity not sufficient for analysis; improper container
Use:
DNA analysis to detect mutations known to cause sickle cell anemia
Limitations:
False-positive and false-negative results may occur for reasons that include genetic variants, blood transfusions, bone marrow transplantation, erroneous representation of family relationships, or contamination of a fetal sample with maternal cells.
